Sr. Program Director - Regulatory and Clinical Development

Akero Therapeutics, a Novo Nordisk company, is a clinical-stage biopharmaceutical organization developing transformational treatments for serious metabolic diseases, including MASH. As Sr. Program Director - Regulatory and Clinical Development, you will lead portfolio strategy, governance, and cross-functional program execution across clinical development initiatives. This executive role ensures alignment between regulatory strategy, operational delivery, and corporate governance while driving high-impact development outcomes.

Akero Therapeutics is seeking a Senior Program Director - Regulatory and Clinical Development to lead strategic program and portfolio execution across its development organization. Reporting to the Vice President of Regulatory Affairs, this role serves as the cross-functional integrator aligning regulatory, clinical, finance, and operational priorities. The position drives governance frameworks, portfolio oversight, and transformation initiatives to ensure successful execution of clinical programs.

Responsibilities:
- Own and execute program and portfolio management strategy across development programs.
- Serve as cross-functional integrator ensuring alignment between strategy, execution, and governance.
- Design and lead development governance frameworks and decision-making processes.
- Oversee integrated development plans, timelines, and milestone delivery.
- Manage portfolio-level risk, issue escalation, and mitigation strategies.
- Partner with Finance and leadership on budgeting, forecasting, and resource allocation.

Requirements:
- Bachelor’s degree required; advanced scientific degree preferred.
- 15+ years of biotech or pharmaceutical portfolio and project management experience.
- Experience supporting Phase III trials, preferably in liver indications.
- Expertise in governance frameworks and strategic decision-making.
- Strong financial acumen and budget management experience.
- Proven leadership in cross-functional team development and organizational transformation.

Benefits:
- Competitive medical, dental, and vision coverage.
- 401(k) savings plan and long-term incentive eligibility.
- Bonus incentive based on company and individual performance.
- Flexible vacation and parental leave policies.

This senior leadership role collaborates extensively with internal teams and external CRO and CMO partners to drive successful clinical development outcomes.